Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | COVID-19 positive (controls include untested)__COVID19-both_sexes-C2_v2-04162021 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL17673, MIXED, INCL. INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS, AND CARDIOFACIOCUTANEOUS SYNDROME |
| Enrichment Score (ES) | 0.51705587 |
| Normalized Enrichment Score (NES) | 1.0960013 |
| Nominal p-value | 0.31062123 |
| FDR q-value | 0.7063219 |
| FWER p-Value | 1.0 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | MAPK3 | 214 | 2.104 | 0.1473 | Yes |
| 2 | SPRED2 | 240 | 2.025 | 0.2991 | Yes |
| 3 | HRAS | 374 | 1.804 | 0.4282 | Yes |
| 4 | SOS1 | 1002 | 1.273 | 0.4897 | Yes |
| 5 | RALGDS | 2526 | 0.809 | 0.4661 | Yes |
| 6 | BRAF | 2674 | 0.782 | 0.5171 | Yes |
| 7 | RRAS2 | 3840 | 0.595 | 0.4972 | No |
| 8 | RRAS | 4425 | 0.526 | 0.5044 | No |
| 9 | MRAS | 6237 | 0.380 | 0.4323 | No |
| 10 | NF1 | 6439 | 0.365 | 0.4488 | No |
| 11 | RASA1 | 6643 | 0.351 | 0.4640 | No |
| 12 | RGL2 | 6731 | 0.346 | 0.4853 | No |
| 13 | ARAF | 7050 | 0.327 | 0.4923 | No |
| 14 | MAP2K1 | 7210 | 0.318 | 0.5075 | No |
| 15 | NRAS | 9130 | 0.228 | 0.4179 | No |
| 16 | RAF1 | 10830 | 0.168 | 0.3359 | No |
| 17 | RALB | 11359 | 0.152 | 0.3181 | No |
| 18 | RASA2 | 12440 | 0.125 | 0.2674 | No |
| 19 | MAP2K2 | 13875 | 0.093 | 0.1945 | No |
| 20 | RALBP1 | 14203 | 0.087 | 0.1829 | No |
| 21 | RAP1A | 14272 | 0.085 | 0.1855 | No |
| 22 | SPRED1 | 14820 | 0.075 | 0.1607 | No |
| 23 | TIAM1 | 14887 | 0.074 | 0.1626 | No |
| 24 | KRAS | 15219 | 0.068 | 0.1493 | No |
| 25 | MAPK1 | 15727 | 0.058 | 0.1255 | No |
